Huey Huang's recent publications with links to pdf files (2003-2008)

T. M. Weiss, P. C. A. van der Wel, J. A. Killian, R. E. Koeppe II, H. W. Huang, “Hydrophobic mismatch between helices and lipid bilayers,” Biophys. J. 84: 379-385 (2003)

P. J. Chen, Y. Liu, T. M. Weiss, H. W. Huang, H. Sinn, E. E. Alp, A. Alatas, A. Said, S. H. Chen. “Studies of short-wavelength collective moleculear motions in lipid bilayers using high resolution inelastic x-ray scattering” Biophysical Chemistry 105, 721-741 (2003)

L. Yang and H. W. Huang. A rhombohedral phase of lipid containing a membrane fusion intermediate structure. Biophys. J. 84, 1808-1817 (2003)

T. M. Weiss, P.-J. Chen2, H. Sinn, E. E. Alp, S.-H. Chen and H. W. Huang, “Collective chain dynamics in lipid bilayers by inelastic x-ray scattering Biophys. J. 84: 3767-3776 (2003)

F. Y. Chen, M. T. Lee and H. W. Huang, “Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation,” Biophys. J. 84: 3751-3758 (2003)

L. Yang, L. Ding and H. W. Huang, “New Phases of Phospholipids and Implications to the membrane fusion problem”, Biochemistry 42: 6631-6635(2003)

L. Ding, L. Yang, T. M. Weiss, A. J. Waring, R. I. Lehrer, and H. W. Huang, “Interaction of antimicrobial peptides with lipopolysaccharides” Biochemistry 42: 12251-12259 (2003).

M. T. Lee, F. Y. Chen and H. W. Huang, "Energetics of pore formation induced by antimicrobial peptides" Biochemistry 43: 3590-3599 (2004).

H. W. Huang, F. Y. Chen and M. T. Lee, "Molecular mechanism of peptide induced pores in membranes" Phys. Rev. Lett. 92: 198304(1-4) (2004).

L. Ding, W. Liu, W. Wang, C. Glinka, D. L. Worcester, L. Yang, and H. W. Huang. "Diffraction techniques for non-lamellar phases of phospholipids." Langmuir 20: 9262-9269 (2004).

L. Ding, T. M. Weiss, G. Fragneto, W. Liu, L. Yang, and H. W. Huang, "Distorted hexagonal phase studied by neutron diffraction: lipid components demixed in a bent monolayer."  Langmuir 21: 203-210 (2005)

M. T. Lee, W. C. Hung, F. Y. Chen and H. W. Huang, “Many-body effect of antimicrobial peptides: On the correlation between lipid’s spontaneous curvature and pore formation” Biophys. J. 89, 4006-4016 (2005)

H. W. Huang, "Diffraction from bilayers" in Encyclopedia of Life Sciences. 2006, on-line publication; npg.els.0003941.

D. Pan, W. Wangchen, W. Liu, L. Yang, and H. W. Huang, “Chain packing in the inverted hexagonal phase of phospholipids: a study by X-ray anomalous diffraction on bromine-labeled chains” J. Am. Chem. Soc. 128: 3800-3807 (2006).

W. Wang, D. Pan, Y. Song, W. Liu, L. Yang and H. W. Huang, “Method of X-ray anomalous diffraction for lipid structures” Biophys. J. 91:736-743 (2006)

H. W. Huang, “Molecular mechanism of antimicrobial peptides: the origin of cooperativity” Biochim. Biophys. Acta 1758, 1292-1302 (2006)

W. Wang, L. Yang and H. W. Huang, “Evidence of cholesterol accumulated in high curvature regions.” Biophys. J. 92:2819-2830 (2007)

W.-C. Hung, M.-T. Lee, F.-Y. Chen and H. W. Huang, “The condensing effect of cholesterol in lipid bilayers” Biophys. J. 92: 3960-3967 (2007)

S. Qian, W. Wang, L. Yang  and H. W. Huang, “Structure of the alamethicin pore reconstructed by x-ray diffraction analysis” Biophys. J. 94: 3512- 3522 (2008)

M. T. Lee, W. C. Hung, F. Y. Chen and H. W. Huang, “Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides.” Proc. Nat. Acad. Sci. U.S.A. 105: 5087-5092 (2008)

W. C. Hung, F. Y. Chen, C. C. Lee, Y. Sun,  M. T. Lee and H. W. Huang. “Membrane thinning effect of curcumin,” Biophys. J. 94: 4331-4338 (2008)

H. W. Huang and L. Yang, “X-ray methods for investigation of structures of lipid assemblies,”  in Handbook of Molecular Biophysics, ed. H. G. Bohr, Wiley-VCH Verlag GmbH & Co. (Weinheim, Germany) Chapter 14, 457-502 (2009)

Y. Sun, C. C. Lee, W.-C. Hung, F-Y Chen, M.-T. Lee and H. W. Huang, “The bound states of amphipathic drugs in lipid bilayers: study of curcumin.” Biophys. J. 95: 2318-2324 (2008)

S. Qian, W. Wang, L. Yang  and H. W. Huang, “Structures of transmembrane pores induced by Bax derived peptides: Evidence for lipidic pores.” Proc. Nat. Acad. Sci. U.S.A. 105: 17379-17383 (2008)

Y. Sun, W.-C. Hung, F.-Y. Chen, C.-C. Lee and H. W. Huang, "Interaction of Tea Catechin (-) Epigallocatechin Gallate with Lipid bilayers." Biophys. J. 96: 1026-1035 (2009)

H. W. Huang, “Free Energies of Molecular Bound States in Lipid Bilayers: Lethal concentrations of Antimicrobial Peptides.” Biophys. J. 92: 3263-3272 ( 2009)

C. C. Lee, Y. Sun and H. W. Huang, "Membrane-mediated Peptide Conformation Change from alpha-Momomers to beta-Aggregates" Biophys. J. 98: 2236-2245 (2010)

Y. Sun, C. C. Lee, T. H. Chen, H. W. Huang, "Kinetic Process of beta-Amyloid Formation via Membrane Binding," Biophys. J. 99: 544-552 (2010)

Y. Sun, C. C. Lee, and H. W. Huang, "Adhesion and Merging of Lipid Bilayers: Method for measuring the free energy of adhesion and hemifusion." Biophys. J. 100: 987-995 (2011)

C. C. Lee, Y. Sun, S. Qian and H. W. Huang, "Transmembrane Pores formed by Human Antimicrobial Peptide LL-37," Biophys. J. 100: 1688-1696 (2011)

S. Qian and H. W. Huang, "A New Phase of Compressed Bilayers That Models the Pre-Stalk Transition State of Membrane Fusion." Biophys. J. 102: 48-55 (2012)

C. C. Lee, Y. Sun and H. W. Huang, "How Type II Diabetes-Related Islet Amloid Polypeptide damages lipid bilayers." Biophys. J. 102: 1059-1068 (2012)

T. L. Sun, Y. Sun, C. C. Lee and H. W. Huang, "Membrane permeability of hydrocarbon-cross-linked peptides" Biophys. J. 104: 1923-1932 (2013)

M. T. Lee, T. L. Sun, W. C. Hung, and H. W. Huang, "Process of inducing pores in membranes by melittin," PNAS 110: 14243-14248 (2013); Supplemental: Movie

Y. F. Chen, T. L. Sun, Y. Sun, and H. W. Huang, "Interacton of daptomycin with lipid bilayers: A lipid extracting effect" Biochemistry 53: 5384-5392 (2014); MovieS1; MovieS2; MovieS3

Y. Sun, T. L. Sun, and H. W. Huang, "Physical states of Escherichia coli spheroplast membranes" Biophys. J. 107: 2082-2090 (2014).

J. E. Faust, T. Desai, A. Verma, I. Ulengin, T.-L. Sun, J. Moss, M. A. Betancourt, Huey W. Huang, T. Lee, J. A. McNew, "The Atlastin C-terminal Tail is an Amphipathic Helix that Perturbs Bilayer Structure during Endoplasmic Reticulum Homotypic Fusion, " J. Biol. Chem. 290:4772-4783 (2015).

Y. Sun, W.-C. Hung, M.-T. Lee, and H. W. Huang, "Membrane-mediated amyloid formation of PrP 106-126: A kinetic study," Biochem. Biophys. Acta 1848:2422-2429 (2016).

W.-C. Hung, M.-T.. Lee, H. Chung, Y.-T. Sun, H. Chen, N. E. Charron, and H. W. Huang, "Comparative Study of the Condensing Effects of Ergosterol and Cholesterol, " Biophys. J. 110: 2026-2033 (2016)

Y. Sun, T. L. Sun and H. W. Huang, "The mode of action of antimicrobial peptides on E. coli spheroplasts," Biophys. J 111:132-139 (2016)

J. E. Faust,  P.-Y. Yang and H. W. Huang, " Action of antimicrobial peptides on bacterial and lipid membranes: a direct comparison," Biophys. J. 112:1663-1672 (2017)

H. W. Huang and N. E. Charron, "Understanding membrane-active antimicrobial peptides," Quart. Rev. Biophys. 50: e10, 1-17 (2017)

M.-T. Lee, W.-C. Hung, M.-H. Hsieh, H. Chen, Y.-Y. Chang and H. W. Huang, "Molecular state of the membrane-active antibiotic daptomycin," Biophys. J. 113:82-90 (2017)