Huey Huang's selected publications with links to pdf files

P. Carruthers and H. W. Huang, "Current Algebra Description of Double-Pion photoproduction," Phys. Lett. 24B, 464-466 (1967).

H. W. Huang, "Chiral Dynamics for High Spin Baryons and An Application to Double-Pion Photoproduction," Phys. Rev. 174, 1799-1808 (1968)

H. W. Huang, "Hydrodynamics of Nematic Liquid Crystals," Phys. Rev. Lett. 26, 1525-1527 (1971).

H. W. Huang and H. J. Morowitz, "A Method for Phenomenological Analysis of Ecological Data," J. Theor. Biol. 35, 489-503 (1972).

H. W. Huang, "Mobility and Diffusion in the Plane of Cell membrane," J. Theor. Biol. 40, 11-17 (1973).

H. W. Huang, "Time Dependent Statistics of the Ising Model in a Magnetic Field," Phys. Rev. A8, 2553-2556 (1973).
H. W. Huang, "Dynamic of the Ising Model," Phys. Lett. 48A, 395-396 (1974).

H. W. Huang, S. H. Hunter, W. K. Warburton, and S. C. Moss, "X-ray Absorption Edge Fine Structure of Potassium Ions in Various Environments:  Application to Frog Blood cells,” Science 204, 191 (1979).  

C. M. Dutta and H. W. Huang, "K-edge Absorption Spectra of Ionic Potassium and Its Z+1 Analogy," Phys. Rev. Lett. 44, 643 (1980); Erratum Phys. Rev. Lett. 45, 851 (1980).

H. W. Huang, "Deformation Free Energy of Bilayer Membrane and Its Effect on Gramicidin Channel Lifetime," Biophys. J. 50,1061-1071 (1986).

H. W. Huang and G. A. Olah, "Uniformly Oriented Gramicidin Channels Embedded in Thick Monodomain Lecithin Multilayers " Biophys. J. 51, 989-992 (1987).

T. Y. Teng, H. W. Huang, and G. A. Olah, "5K Extended X-ray Absorption Fine Structure and   40K 10-s Resolved Extended X-ray Absorption Fine Structure Studies of Photolyzed   Carboxymyoglobin," Biochemistry 26, 8066-8072 (1987).

G. A. Olah and H. W. Huang "Circular Dichroism of Oriented a-Helices.  I.  Proof of the Exciton Theory," J. Chem. Phys. 89, 2531-2538 (1988).

G. A. Olah and H. W. Huang, "Circular Dichroism of Oriented a-Helices.  II.  Electric Field Oriented Polypeptides,” J. Chem. Phys. 89, 6956-6962 (1988).

Y. Wu, H. W. Huang, and G. A. Olah, "Method of Oriented Circular Dichroism,” Biophys. J. 57, 797-806 (1990).

G. A. Olah, H. W. Huang, W. Liu and Y. Wu, "Location of Ion Binding Sites in the Gramicidin Channel by X-ray Diffraction." J. Mol. Biol. 218, 847-858 (1991).

Liu, W., T. Y. Teng, Y. Wu, and H. W. Huang, “Phase Determination for Membrane Diffraction by Anomalous Dispersion.” Acta Cryst. A47, 553-559 (1991).


T. M. Weiss, P. C. A. van der Wel, J. A. Killian, R. E. Koeppe II, H. W. Huang, “Hydrophobic mismatch between helices and lipid bilayers,” Biophys. J. 84: 379-385 (2003)

P. J. Chen, Y. Liu, T. M. Weiss, H. W. Huang, H. Sinn, E. E. Alp, A. Alatas, A. Said, S. H. Chen. “Studies of short-wavelength collective moleculear motions in lipid bilayers using high resolution inelastic x-ray scattering” Biophysical Chemistry 105, 721-741 (2003)

L. Yang and H. W. Huang. A rhombohedral phase of lipid containing a membrane fusion intermediate structure. Biophys. J. 84, 1808-1817 (2003)

T. M. Weiss, P.-J. Chen2, H. Sinn, E. E. Alp, S.-H. Chen and H. W. Huang, “Collective chain dynamics in lipid bilayers by inelastic x-ray scattering Biophys. J. 84: 3767-3776 (2003)

F. Y. Chen, M. T. Lee and H. W. Huang, “Evidence for membrane thinning effect as the mechanism for peptide-induced pore formation,” Biophys. J. 84: 3751-3758 (2003)

L. Yang, L. Ding and H. W. Huang, “New Phases of Phospholipids and Implications to the membrane fusion problem”, Biochemistry 42: 6631-6635(2003)

L. Ding, L. Yang, T. M. Weiss, A. J. Waring, R. I. Lehrer, and H. W. Huang, “Interaction of antimicrobial peptides with lipopolysaccharides” Biochemistry 42: 12251-12259 (2003).

M. T. Lee, F. Y. Chen and H. W. Huang, "Energetics of pore formation induced by antimicrobial peptides" Biochemistry 43: 3590-3599 (2004).

H. W. Huang, F. Y. Chen and M. T. Lee, "Molecular mechanism of peptide induced pores in membranes" Phys. Rev. Lett. 92: 198304(1-4) (2004).

L. Ding, W. Liu, W. Wang, C. Glinka, D. L. Worcester, L. Yang, and H. W. Huang. "Diffraction techniques for non-lamellar phases of phospholipids." Langmuir 20: 9262-9269 (2004).

L. Ding, T. M. Weiss, G. Fragneto, W. Liu, L. Yang, and H. W. Huang, "Distorted hexagonal phase studied by neutron diffraction: lipid components demixed in a bent monolayer."  Langmuir 21: 203-210 (2005)

M. T. Lee, W. C. Hung, F. Y. Chen and H. W. Huang, “Many-body effect of antimicrobial peptides: On the correlation between lipid’s spontaneous curvature and pore formation” Biophys. J. 89, 4006-4016 (2005)

H. W. Huang, "Diffraction from bilayers" in Encyclopedia of Life Sciences. 2006, on-line publication http://www.els.net; npg.els.0003941.

D. Pan, W. Wangchen, W. Liu, L. Yang, and H. W. Huang, “Chain packing in the inverted hexagonal phase of phospholipids: a study by X-ray anomalous diffraction on bromine-labeled chains” J. Am. Chem. Soc. 128: 3800-3807 (2006).

W. Wang, D. Pan, Y. Song, W. Liu, L. Yang and H. W. Huang, “Method of X-ray anomalous diffraction for lipid structures” Biophys. J. 91:736-743 (2006)

H. W. Huang, “Molecular mechanism of antimicrobial peptides: the origin of cooperativity” Biochim. Biophys. Acta 1758, 1292-1302 (2006)

W. Wang, L. Yang and H. W. Huang, “Evidence of cholesterol accumulated in high curvature regions.” Biophys. J. 92:2819-2830 (2007)

W.-C. Hung, M.-T. Lee, F.-Y. Chen and H. W. Huang, “The condensing effect of cholesterol in lipid bilayers” Biophys. J. 92: 3960-3967 (2007)

S. Qian, W. Wang, L. Yang  and H. W. Huang, “Structure of the alamethicin pore reconstructed by x-ray diffraction analysis” Biophys. J. 94: 3512- 3522 (2008)

M. T. Lee, W. C. Hung, F. Y. Chen and H. W. Huang, “Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides.” Proc. Nat. Acad. Sci. U.S.A. 105: 5087-5092 (2008)

W. C. Hung, F. Y. Chen, C. C. Lee, Y. Sun,  M. T. Lee and H. W. Huang. “Membrane thinning effect of curcumin,” Biophys. J. 94: 4331-4338 (2008)

H. W. Huang and L. Yang, “X-ray methods for investigation of structures of lipid assemblies,”  in Handbook of Molecular Biophysics, ed. H. G. Bohr, Wiley-VCH Verlag GmbH & Co. (Weinheim, Germany) Chapter 14, 457-502 (2009)

Y. Sun, C. C. Lee, W.-C. Hung, F-Y Chen, M.-T. Lee and H. W. Huang, “The bound states of amphipathic drugs in lipid bilayers: study of curcumin.” Biophys. J. 95: 2318-2324 (2008)

S. Qian, W. Wang, L. Yang  and H. W. Huang, “Structures of transmembrane pores induced by Bax derived peptides: Evidence for lipidic pores.” Proc. Nat. Acad. Sci. U.S.A. 105: 17379-17383 (2008)

Y. Sun, W.-C. Hung, F.-Y. Chen, C.-C. Lee and H. W. Huang, "Interaction of Tea Catechin (-) Epigallocatechin Gallate with Lipid bilayers." Biophys. J. 96: 1026-1035 (2009)

H. W. Huang, “Free Energies of Molecular Bound States in Lipid Bilayers: Lethal concentrations of Antimicrobial Peptides.” Biophys. J. 92: 3263-3272 ( 2009)

C. C. Lee, Y. Sun and H. W. Huang, "Membrane-mediated Peptide Conformation Change from alpha-Momomers to beta-Aggregates" Biophys. J. 98: 2236-2245 (2010)

Y. Sun, C. C. Lee, T. H. Chen, H. W. Huang, "Kinetic Process of beta-Amyloid Formation via Membrane Binding," Biophys. J. 99: 544-552 (2010)

Y. Sun, C. C. Lee, and H. W. Huang, "Adhesion and Merging of Lipid Bilayers: Method for measuring the free energy of adhesion and hemifusion." Biophys. J. 100: 987-995 (2011)

C. C. Lee, Y. Sun, S. Qian and H. W. Huang, "Transmembrane Pores formed by Human Antimicrobial Peptide LL-37," Biophys. J. 100: 1688-1696 (2011)

S. Qian and H. W. Huang, "A New Phase of Compressed Bilayers That Models the Pre-Stalk Transition State of Membrane Fusion." Biophys. J. 102: 48-55 (2012)

C. C. Lee, Y. Sun and H. W. Huang, "How Type II Diabetes-Related Islet Amloid Polypeptide damages lipid bilayers." Biophys. J. 102: 1059-1068 (2012)

T. L. Sun, Y. Sun, C. C. Lee and H. W. Huang, "Membrane permeability of hydrocarbon-cross-linked peptides" Biophys. J. 104: 1923-1932 (2013)

M. T. Lee, T. L. Sun, W. C. Hung, and H. W. Huang, "Process of inducing pores in membranes by melittin," PNAS 110: 14243-14248 (2013); Supplemental: Movie

Y. F. Chen, T. L. Sun, Y. Sun, and H. W. Huang, "Interacton of daptomycin with lipid bilayers: A lipid extracting effect" Biochemistry 53: 5384-5392 (2014); MovieS1; MovieS2; MovieS3

Y. Sun, T. L. Sun, and H. W. Huang, "Physical states of Escherichia coli spheroplast membranes" Biophys. J. 107: 2082-2090 (2014).

J. E. Faust, T. Desai, A. Verma, I. Ulengin, T.-L. Sun, J. Moss, M. A. Betancourt, Huey W. Huang, T. Lee, J. A. McNew, "The Atlastin C-terminal Tail is an Amphipathic Helix that Perturbs Bilayer Structure during Endoplasmic Reticulum Homotypic Fusion, " J. Biol. Chem. 290:4772-4783 (2015).

Y. Sun, W.-C. Hung, M.-T. Lee, and H. W. Huang, "Membrane-mediated amyloid formation of PrP 106-126: A kinetic study," Biochem. Biophys. Acta 1848:2422-2429 (2016).

W.-C. Hung, M.-T.. Lee, H. Chung, Y.-T. Sun, H. Chen, N. E. Charron, and H. W. Huang, "Comparative Study of the Condensing Effects of Ergosterol and Cholesterol, " Biophys. J. 110: 2026-2033 (2016)

Y. Sun, T. L. Sun and H. W. Huang, "The mode of action of antimicrobial peptides on E. coli spheroplasts," Biophys. J 111:132-139 (2016)

J. E. Faust,  P.-Y. Yang and H. W. Huang, " Action of antimicrobial peptides on bacterial and lipid membranes: a direct comparison," Biophys. J. 112:1663-1672 (2017)

H. W. Huang and N. E. Charron, "Understanding membrane-active antimicrobial peptides," Quart. Rev. Biophys. 50: e10, 1-17 (2017)

M.-T. Lee, W.-C. Hung, M.-H. Hsieh, H. Chen, Y.-Y. Chang and H. W. Huang, "Molecular state of the membrane-active antibiotic daptomycin," Biophys. J. 113:82-90 (2017)

M.-T. Lee, P.-Y. Yang, N. E. Charron, M.-H. Hsieh, Y.-Y. Chang,  H. W. Huang, “Comparison of the Effects of Daptomycin on Bacterial and Model Membranes” Biochemistry, 57:5629-5639 (2018)

M.-T. Lee, W.-C. Hung and H. W. Huang, “Rhombohedral trap for studying molecular oligomerization in membranes: application to daptomycin,” Soft Matter 15, 4326 – 4333 (2019)