Research Interests
Antimicrobial Peptides:
Mechanism of AMP
Energetics of Pore Formation
Toroidal vs. Barrel Stave Model
Observation of Pores
Peptide Orientation Change
Membrane Thinning Effect
Concentration Dependence
Experimental Methods:
Oriented Circular Dichroism
In-plane Scattering
Diffraction Techniques
Lipid Dynamics by IXS
Anomalous Diffraction
Peptide-Lipid Interact:
Hydrophobic Matching
Membrane-mediated Protein Interactions
Elasticity Theory and Thermodynamics
Fusion and Lipids:
Bending & Lipid Demixing
Chain Volume Conservation
LPS and others
Gramicidin Problems:
Channel Poperties
Model Studies
Huey W. Huang - Sam and Helen Worden Chair Professor
Department of Physics & Astronomy - Rice University - phone: 713-348-4889 - fax: 713-348-4150

Lipid Dynamics by IXS

S. H. Chen, C. Y. Liao, H. W. Huang, T. M. Weiss, M. C. Bellisent-Funel, F. Sette, “The collective dynamics in fully hydrated phospholipid bilayers studied by inelastic x-ray scattering,” Phys. Rev. Lett. 86: 740-743 (2001).

T. M. Weiss, P.-J. Chen, H. Sinn, E. E. Alp, S.-H. Chen and H. W. Huang, “Collective chain dynamics in lipid bilayers by inelastic x-ray scattering Biophys. J. 84: 3767-3776 (2003)

P. J. Chen, Y. Liu, T. M. Weiss, H. W. Huang, H. Sinn, E. E. Alp, A. Alatas, A. Said, S. H. Chen. “Studies of short-wavelength collective moleculear motions in lipid bilayers using high resolution inelastic x-ray scattering” Biophysical Chemistry 105, 721-741 (2003)